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Effect of Roux-en-Y Gastric Bypass on the NLRP3 Inflammasome in Adipose Tissue from Obese Rats

OBJECTIVE: Obesity is associated with low-grade chronic inflammation. We hypothesized that Roux-en-Y gastric bypass (RYGB) surgery would reduce activation of the NLRP3 inflammasome in metabolically active adipose tissue (AT) of obese rats, and this change would be related to decreases in body weight...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mocanu, Andreea Oana, Mulya, Anny, Huang, Hazel, Dan, Olivia, Shimizu, Hideharu, Batayyah, Esam, Brethauer, Stacy A., Dinischiotu, Anca, Kirwan, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593548/
https://ncbi.nlm.nih.gov/pubmed/26437377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139764
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