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Shifts in macrophage phenotype at the biomaterial interface via IL-4 eluting coatings are associated with improved implant integration
The present study tests the hypothesis that transient, early-stage shifts in macrophage polarization at the tissue-implant interface from a pro-inflammatory (M1) to an anti-inflammatory/regulatory (M2) phenotype mitigates the host inflammatory reaction against a non-degradable polypropylene mesh mat...
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| Publicado en: | Biomaterials |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5121003/ https://ncbi.nlm.nih.gov/pubmed/27760399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.10.019 |
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