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Shifts in macrophage phenotype at the biomaterial interface via IL-4 eluting coatings are associated with improved implant integration

The present study tests the hypothesis that transient, early-stage shifts in macrophage polarization at the tissue-implant interface from a pro-inflammatory (M1) to an anti-inflammatory/regulatory (M2) phenotype mitigates the host inflammatory reaction against a non-degradable polypropylene mesh mat...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Hachim, Daniel, LoPresti, Samuel T., Yates, Cecelia C., Brown, Bryan N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121003/
https://ncbi.nlm.nih.gov/pubmed/27760399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.10.019
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