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Distinct Release Strategies are Required to Modulate Macrophage Phenotype in Young Versus Aged Animals

The role of innate immunity and macrophages in the host response to biomaterials has received renewed attention. A context-dependent spectrum of macrophage phenotypes are shown to affect tissue integration and performance of implanted biomaterials and medical devices. Recent studies by our group dem...

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Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Hachim, Daniel, Iftikhar, Aimon, LoPresti, Samuel T., Nolfi, Alexis L., Ravichandar, Shweta, Skillen, Clint, Brown, Bryan N.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6602858/
https://ncbi.nlm.nih.gov/pubmed/31103676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2019.05.020
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