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Synonymous Co-Variation across the E1/E2 Gene Junction of Hepatitis C Virus Defines Virion Fitness

Hepatitis C virus is a positive-sense single-stranded RNA virus. The gene junction partitioning the viral glycoproteins E1 and E2 displays concurrent sequence evolution with the 3′-end of E1 highly conserved and the 5′-end of E2 highly heterogeneous. This gene junction is also believed to contain st...

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Vydáno v:PLoS One
Hlavní autoři: Palmer, Brendan A., Fanning, Liam J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120871/
https://ncbi.nlm.nih.gov/pubmed/27880830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167089
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