Phenotypic characterization of a comprehensive set of MAPK1/ERK2 missense mutants

Tumor-specific genomic information has the potential to guide therapeutic strategies and revolutionize patient treatment. Currently, this approach is limited by an abundance of disease-associated mutants whose biological functions and impacts on therapeutic response are uncharacterized. To begin to...

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Udgivet i:Cell Rep
Main Authors: Brenan, Lisa, Andreev, Aleksandr, Cohen, Ofir, Pantel, Sasha, Kamburov, Atanas, Cacchiarelli, Davide, Persky, Nicole S., Zhu, Cong, Bagul, Mukta, Goetz, Eva M., Burgin, Alex B., Garraway, Levi A., Getz, Gad, Mikkelsen, Tarjei S., Piccioni, Federica, Root, David E., Johannessen, Cory M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120861/
https://ncbi.nlm.nih.gov/pubmed/27760319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.061
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