Isolation of a Defective Prion Mutant from Natural Scrapie

It is widely known that prion strains can mutate in response to modification of the replication environment and we have recently reported that prion mutations can occur in vitro during amplification of vole-adapted prions by Protein Misfolding Cyclic Amplification on bank vole substrate (bvPMCA). He...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Pathog
Main Authors: Vanni, Ilaria, Migliore, Sergio, Cosseddu, Gian Mario, Di Bari, Michele Angelo, Pirisinu, Laura, D’Agostino, Claudia, Riccardi, Geraldina, Agrimi, Umberto, Nonno, Romolo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120856/
https://ncbi.nlm.nih.gov/pubmed/27880822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006016
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