Molecular Discrimination of Sheep Bovine Spongiform Encephalopathy from Scrapie

Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrP(Sc) from sheep BSE is extremely resistant to denaturation. This feature, combined with the N-terminal PrP(Sc)...

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Main Authors: Pirisinu, Laura, Migliore, Sergio, Di Bari, Michele Angelo, Esposito, Elena, Baron, Thierry, D’Agostino, Claudia, De Grossi, Luigi, Vaccari, Gabriele, Agrimi, Umberto, Nonno, Romolo
Format: Artigo
Sprog:Inglês
Udgivet: Centers for Disease Control and Prevention 2011
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377410/
https://ncbi.nlm.nih.gov/pubmed/21470463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid1704.101215
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