Prion Protein Alleles Showing a Protective Effect on the Susceptibility of Sheep to Scrapie and Bovine Spongiform Encephalopathy

The susceptibility of sheep to classical scrapie and bovine spongiform encephalopathy (BSE) is mainly influenced by prion protein (PrP) polymorphisms A136V, R154H, and Q171R, with the ARR allele associated with significantly decreased susceptibility. Here we report the protective effect of the amino...

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Detalhes bibliográficos
Main Authors: Vaccari, Gabriele, D'Agostino, Claudia, Nonno, Romolo, Rosone, Francesca, Conte, Michela, Di Bari, Michele Angelo, Chiappini, Barbara, Esposito, Elena, De Grossi, Luigi, Giordani, Francesco, Marcon, Stefano, Morelli, Luisella, Borroni, Renata, Agrimi, Umberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933282/
https://ncbi.nlm.nih.gov/pubmed/17442723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02880-06
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