Prion Protein Alleles Showing a Protective Effect on the Susceptibility of Sheep to Scrapie and Bovine Spongiform Encephalopathy

The susceptibility of sheep to classical scrapie and bovine spongiform encephalopathy (BSE) is mainly influenced by prion protein (PrP) polymorphisms A136V, R154H, and Q171R, with the ARR allele associated with significantly decreased susceptibility. Here we report the protective effect of the amino...

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Bibliografiska uppgifter
Huvudupphovsmän: Vaccari, Gabriele, D'Agostino, Claudia, Nonno, Romolo, Rosone, Francesca, Conte, Michela, Di Bari, Michele Angelo, Chiappini, Barbara, Esposito, Elena, De Grossi, Luigi, Giordani, Francesco, Marcon, Stefano, Morelli, Luisella, Borroni, Renata, Agrimi, Umberto
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933282/
https://ncbi.nlm.nih.gov/pubmed/17442723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02880-06
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