Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model

The antiviral properties of iminosugars have been reported previously in vitro and in small animal models against Ebola virus (EBOV); however, their effects have not been tested in larger animal models such as guinea pigs. We tested the iminosugars N-butyl-deoxynojirimycin (NB-DNJ) and N-(9-methoxyn...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Miller, Joanna L., Spiro, Simon G., Dowall, Stuart D., Taylor, Irene, Rule, Antony, Alonzi, Dominic S., Sayce, Andrew C., Wright, Edward, Bentley, Emma M., Thom, Ruth, Hall, Graham, Dwek, Raymond A., Hewson, Roger, Zitzmann, Nicole
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120828/
https://ncbi.nlm.nih.gov/pubmed/27880800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167018
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