Minimal In Vivo Efficacy of Iminosugars in a Lethal Ebola Virus Guinea Pig Model

The antiviral properties of iminosugars have been reported previously in vitro and in small animal models against Ebola virus (EBOV); however, their effects have not been tested in larger animal models such as guinea pigs. We tested the iminosugars N-butyl-deoxynojirimycin (NB-DNJ) and N-(9-methoxyn...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS One
المؤلفون الرئيسيون: Miller, Joanna L., Spiro, Simon G., Dowall, Stuart D., Taylor, Irene, Rule, Antony, Alonzi, Dominic S., Sayce, Andrew C., Wright, Edward, Bentley, Emma M., Thom, Ruth, Hall, Graham, Dwek, Raymond A., Hewson, Roger, Zitzmann, Nicole
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2016
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120828/
https://ncbi.nlm.nih.gov/pubmed/27880800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167018
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