Caricamento...
Disruption of PCNA-lamins A/C interactions by prelamin A induces DNA replication fork stalling
The accumulation of prelamin A is linked to disruption of cellular homeostasis, tissue degeneration and aging. Its expression is implicated in compromised genome stability and increased levels of DNA damage, but to date there is no complete explanation for how prelamin A exerts its toxic effects. As...
Salvato in:
| Pubblicato in: | Nucleus |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120601/ https://ncbi.nlm.nih.gov/pubmed/27676213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1239685 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|