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Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid

We hypothesized that one mechanism underlying the association between obstructive sleep apnea (OSA) and Alzheimer Disease is OSA leading to decreased slow wave activity, increased synaptic activity, decreased glymphatic clearance, and increased amyloid-β. Polysomnography and lumbar puncture were per...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Ann Neurol
Päätekijät: Ju, Yo-El S., Finn, Mary Beth, Sutphen, Courtney L., Herries, Elizabeth M., Jerome, Gina M., Ladenson, Jack H., Crimmins, Daniel L., Fagan, Anne M., Holtzman, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120585/
https://ncbi.nlm.nih.gov/pubmed/27129429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24672
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