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Obstructive sleep apnea decreases central nervous system-derived proteins in the cerebrospinal fluid
We hypothesized that one mechanism underlying the association between obstructive sleep apnea (OSA) and Alzheimer Disease is OSA leading to decreased slow wave activity, increased synaptic activity, decreased glymphatic clearance, and increased amyloid-β. Polysomnography and lumbar puncture were per...
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| Publicado no: | Ann Neurol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5120585/ https://ncbi.nlm.nih.gov/pubmed/27129429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24672 |
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