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Thrombotic Stroke: Neuroprotective Therapy by Recombinant Activated Protein C
Activated protein C (APC), derived from the plasma protease zymogen, protein C, is antithrombotic and anti-inflammatory. In preclinical injury models, recombinant APC provides neuroprotection for multiple injuries, including ischemic stroke. APC acts directly on brain endothelial cells and neurons b...
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Pubblicato in: | Arterioscler Thromb Vasc Biol |
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Autori principali: | , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5119536/ https://ncbi.nlm.nih.gov/pubmed/27758767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.308038 |
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