Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study

OBJECTIVE: Rapamycin analogs have reproducible but modest efficacy in endometrial cancer (EC). Identification of molecular biomarkers that predict benefit could guide clinical development. METHODS: Fixed primary tissue and whole blood were collected prospectively from patients enrolled on GOG 248. D...

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書誌詳細
出版年:Gynecol Oncol
主要な著者: Myers, Andrea P., Filiaci, Virginia L., Zhang, Yuping, Pearl, Michael, Behbakht, Kian, Makker, Vicky, Hanjani, Parviz, Zweizig, Susan, Burke, James J., Downey, Gordon, Leslie, Kimberly K., Van Hummelen, Paul, Birrer, Michael J., Fleming, Gini F.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119517/
https://ncbi.nlm.nih.gov/pubmed/27016228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2016.02.025
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