The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation

Metabolic stress induces autophagy as an alternative source of energy and metabolites. Insufficient autophagy in nutrient-deprived cancer cells would be beneficial for cancer therapy. Here, we performed a functional screen in search of novel autophagy regulators from natural products. We showed that...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lao, Yuanzhi, Wan, Gang, Liu, Zhenyan, Wang, Xiaoyu, Ruan, Ping, Xu, Wei, Xu, Danqing, Xie, Weidong, Zhang, Yaou, Xu, Hongxi, Xu, Naihan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119057/
https://ncbi.nlm.nih.gov/pubmed/24642486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.28034
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