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Serum and nutrient deprivation increases autophagic flux in intervertebral disc annulus fibrosus cells: an in-vitro experimental study

PURPOSE: The loss of nutrient supply is a suspected contributor of intervertebral disc degeneration. However, the extent to which low nutrition affects disc annulus fibrosus (AF) cells is unknown as nutrient deprivation has mainly been investigated in disc nucleus pulposus cells. Hence, an experimen...

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Vydáno v:Eur Spine J
Hlavní autoři: Yurube, Takashi, Buchser, William J., Moon, Hong Joo, Hartman, Robert A., Takayama, Koji, Kawakami, Yohei, Nishida, Kotaro, Kurosaka, Masahiro, Vo, Nam V., Kang, James D., Lotze, Michael T., Sowa, Gwendolyn A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538458/
https://ncbi.nlm.nih.gov/pubmed/30847707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-019-05910-9
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