The Natural Compound Oblongifolin C Exhibits Anticancer Activity by Inhibiting HSPA8 and Cathepsin B In Vitro

PPAPs (Polycyclic polyprenylated acylphloroglucinols) are a class of compounds with diverse bioactivities, including anticancer effects. Oblongifolin C (OC) is a PPAP isolated from the plant of Garcinia yunnanensis Hu. We previously discovered that OC induces apoptosis, inhibits autophagic flux, and...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Han, Li, Xu, Danqing, Xi, Zhichao, Wu, Man, Nik Nabil, Wan Najbah, Zhang, Juan, Sui, Hua, Fu, Wenwei, Zhou, Hua, Lao, Yuanzhi, Xu, Gang, Guo, Cheng, Xu, Hongxi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2020
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7773843/
https://ncbi.nlm.nih.gov/pubmed/33390942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.564833
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