Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways

Gemcitabine (GEM)-induced drug resistance is the major reason for the failure of chemotherapy in pancreatic cancer (PC). In this study, we found that Oblongifolin C (OC) efficiently inhibited PC cell proliferation by inducing G0/G1 arrest and apoptosis. Also, our mechanism study demonstrated that OC...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Li, Yang, Xi, Zhichao, Chen, Xiaoqiong, Cai, Shuangfan, Liang, Chen, Wang, Zhen, Li, Yingyi, Tan, Hongsheng, Lao, Yuanzhi, Xu, Hongxi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970202/
https://ncbi.nlm.nih.gov/pubmed/29749405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0574-1
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados