Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles, and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China

Ethambutol (EMB) is an essential first-line drug for tuberculosis (TB) treatment. Nucleotide substitutions at embB codon 306 (embB306) have been proposed to be a potential marker for EMB resistance and a predictor of broad drug resistance in clinical Mycobacterium tuberculosis isolates. However, dis...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Li, Yanan, Wang, Yuling, Zhang, Zhi, Gao, Huixia, Wang, Haibin, Cao, Jinfeng, Zhang, Shumin, Liu, Yuzhen, Lu, Jianhua, Xu, Zungui, Dai, Erhei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119010/
https://ncbi.nlm.nih.gov/pubmed/27671062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00532-16
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