A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10

Hereditary hemorrhagic telangiectasia (HHT) is a potentially life-threatening genetic vascular disorder caused by loss-of-function mutations in the genes encoding activin receptor-like kinase 1 (ALK1), endoglin, Smad4, and bone morphogenetic protein 9 (BMP9). Injections of mouse neonates with BMP9/1...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ruiz, Santiago, Zhao, Haitian, Chandakkar, Pallavi, Chatterjee, Prodyot K., Papoin, Julien, Blanc, Lionel, Metz, Christine N., Campagne, Fabien, Marambaud, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118799/
https://ncbi.nlm.nih.gov/pubmed/27874028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37366
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