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Beyond Antibodies: Development of a Novel Protein Scaffold Based on Human Chaperonin 10
Human Chaperonin 10 (hCpn10) was utilised as a novel scaffold for presenting peptides of therapeutic and diagnostic significance. Molecular dynamic simulations and protein sizing analyses identified a peptide linker (P1) optimal for the formation of the quarternary hCpn10 heptamer structure. hCpn10...
Enregistré dans:
Publié dans: | Sci Rep |
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Auteurs principaux: | , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
Nature Publishing Group
2016
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118791/ https://ncbi.nlm.nih.gov/pubmed/27874025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37348 |
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