Nanocell targeting using engineered bispecific antibodies

There are many design formats for bispecific antibodies (BsAbs), and the best design choice is highly dependent on the final application. Our aim was to engineer BsAbs to target a novel nanocell (EnGeneIC Delivery Vehicle or EDV(TM)nanocell) to the epidermal growth factor receptor (EGFR). EDV(TM)nan...

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Vydáno v:MAbs
Hlavní autoři: Taylor, Karin, Howard, Christopher B, Jones, Martina L, Sedliarou, Ilya, MacDiarmid, Jennifer, Brahmbhatt, Himanshu, Munro, Trent P, Mahler, Stephen M
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622061/
https://ncbi.nlm.nih.gov/pubmed/25523746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.985952
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