Targeting membrane proteins for antibody discovery using phage display

A critical factor in the successful isolation of new antibodies by phage display is the presentation of a correctly folded antigen. While this is relatively simple for soluble proteins which can be purified and immobilized onto a plastic surface, membrane proteins offer significant challenges for an...

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Udgivet i:Sci Rep
Main Authors: Jones, Martina L., Alfaleh, Mohamed A., Kumble, Sumukh, Zhang, Shuo, Osborne, Geoffrey W., Yeh, Michael, Arora, Neetika, Hou, Jeff Jia Cheng, Howard, Christopher B., Chin, David Y., Mahler, Stephen M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870581/
https://ncbi.nlm.nih.gov/pubmed/27189586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26240
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