Antimicrobial Peptide Potency is Facilitated by Greater Conformational Flexibility when Binding to Gram-negative Bacterial Inner Membranes

The interaction of antimicrobial peptides (AMPs) with the inner membrane of Gram-negative bacteria is a key determinant of their abilities to exert diverse bactericidal effects. Here we present a molecular level understanding of the initial target membrane interaction for two cationic α-helical AMPs...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Amos, Sarah-Beth T. A., Vermeer, Louic S., Ferguson, Philip M., Kozlowska, Justyna, Davy, Matthew, Bui, Tam T., Drake, Alex F., Lorenz, Christian D., Mason, A. James
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118786/
https://ncbi.nlm.nih.gov/pubmed/27874065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37639
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares