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Blood–Brain Barrier Disruption and Neurovascular Unit Dysfunction in Diabetic Mice: Protection with the Mitochondrial Carbonic Anhydrase Inhibitor Topiramate

All forms of diabetes mellitus are characterized by chronic hyperglycemia, resulting in the development of a number of microvascular and macrovascular pathologies. Diabetes is also associated with changes in brain microvasculature, leading to dysfunction and ultimately disruption of the blood–brain...

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Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Salameh, Therese S., Shah, Gul N., Price, Tulin O., Hayden, Melvin R., Banks, William A.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118649/
https://ncbi.nlm.nih.gov/pubmed/27729477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.237057
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