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Effects of acetaminophen on mitochondrial complex I activity in the rat liver and kidney: a PET study with (18)F-BCPP-BF
BACKGROUND: In the present study, 2-tert-butyl-4-chloro-5-[6-(4-(18)F-fluorobutoxy)-pyridin-3-ylmethoxy]-2H-pyridazin-3-one ((18)F-BCPP-BF), a PET probe for mitochondrial complex I (MC-I), was used to validate whether MC-I is a useful biomarker for detecting acetaminophen-induced dysfunctions in the...
Shranjeno v:
| izdano v: | EJNMMI Res |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5118230/ https://ncbi.nlm.nih.gov/pubmed/27873239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0241-4 |
| Oznake: |
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