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Theoretical modeling of multiprotein complexes by iSPOT: Integration of small-angle X-ray scattering, hydroxyl radical footprinting, and computational docking

Structural determination of protein-protein complexes such as multidomain nuclear receptors has been challenging for high-resolution structural techniques. Here, we present a combined use of multiple biophysical methods, termed iSPOT, an integration of shape information from small-angle X-ray scatte...

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Détails bibliographiques
Publié dans:J Struct Biol
Auteurs principaux: Huang, Wei, Ravikumar, Krishnakumar M., Parisien, Marc, Yang, Sichun
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118146/
https://ncbi.nlm.nih.gov/pubmed/27496803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2016.08.001
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