Optogenetics enables functional analysis of human embryonic stem cell–derived grafts in a Parkinson’s disease model

Recent studies have shown evidence of behavioral recovery after transplantation of human pluripotent stem cell (PSC)-derived neural cells in animal models of neurological disease(1–4). However, little is known about the mechanisms underlying graft function. Here we use optogenetics to modulate in re...

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Detaylı Bibliyografya
Yayımlandı:Nat Biotechnol
Asıl Yazarlar: Steinbeck, Julius A, Choi, Se Joon, Mrejeru, Ana, Ganat, Yosif, Deisseroth, Karl, Sulzer, David, Mosharov, Eugene V, Studer, Lorenz
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117952/
https://ncbi.nlm.nih.gov/pubmed/25580598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3124
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