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Optogenetics enables functional analysis of human embryonic stem cell–derived grafts in a Parkinson’s disease model

Recent studies have shown evidence of behavioral recovery after transplantation of human pluripotent stem cell (PSC)-derived neural cells in animal models of neurological disease(1–4). However, little is known about the mechanisms underlying graft function. Here we use optogenetics to modulate in re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Biotechnol
Prif Awduron: Steinbeck, Julius A, Choi, Se Joon, Mrejeru, Ana, Ganat, Yosif, Deisseroth, Karl, Sulzer, David, Mosharov, Eugene V, Studer, Lorenz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117952/
https://ncbi.nlm.nih.gov/pubmed/25580598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3124
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