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ATP Hydrolysis Induced Conformational Changes in the Vitamin B(12) Transporter BtuCD Revealed by MD Simulations
ATP binding cassette (ABC) transporters utilize the energy of ATP hydrolysis to uni-directionally transport substrates across cell membrane. ATP hydrolysis occurs at the nucleotide-binding domain (NBD) dimer interface of ABC transporters, whereas substrate translocation takes place at the translocat...
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| Udgivet i: | PLoS One |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117765/ https://ncbi.nlm.nih.gov/pubmed/27870912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166980 |
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