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ATP Hydrolysis Induced Conformational Changes in the Vitamin B(12) Transporter BtuCD Revealed by MD Simulations

ATP binding cassette (ABC) transporters utilize the energy of ATP hydrolysis to uni-directionally transport substrates across cell membrane. ATP hydrolysis occurs at the nucleotide-binding domain (NBD) dimer interface of ABC transporters, whereas substrate translocation takes place at the translocat...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Pan, Chao, Weng, Jingwei, Wang, Wenning
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117765/
https://ncbi.nlm.nih.gov/pubmed/27870912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166980
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