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Philadelphia chromosome duplication as a ring-shaped chromosome
The gain of a second copy of the Philadelphia chromosome is one of the main secondary chromosomal changes related to the clonal evolution of cells with t(9;22) in chronic myelogenous leukemia. This gain causes the acquisition of another copy of the BCR/ABL1 fusion gene. Isochromosomes of the der(22)...
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| Publicado no: | Mol Cytogenet |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117599/ https://ncbi.nlm.nih.gov/pubmed/27895712 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-016-0292-2 |
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