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Are submicroscopic chromosomal inversions predisposing factors for the t(9;22)(q34;q11.2) translocation in chronic myeloid leukemia?

A complex chromosomal rearrangement observed in a patient with chronic myeloid leukemia was explained as the consequence of a multistep process. The explanation involved an initial t(9;22) translocation with breakpoints distant from the BCR and ABL1 genes followed by genomic deletions that produced...

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Bibliographic Details
Published in:Mol Cytogenet
Main Authors: González García, Juan Ramón, Cruz, Martín Daniel Domínguez, Gutiérrez, César Borjas
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348163/
https://ncbi.nlm.nih.gov/pubmed/25741382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13039-015-0116-9
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