Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model

Holoprosencephaly (HPE) is a common and severe human developmental abnormality marked by malformations of the forebrain and face. Although several genetic mutations have been linked to HPE, phenotypic outcomes range dramatically, and most cases cannot be attributed to a specific cause. Gene-environm...

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Bibliografische gegevens
Gepubliceerd in:Dis Model Mech
Hoofdauteurs: Heyne, Galen W., Everson, Joshua L., Ansen-Wilson, Lydia J., Melberg, Cal G., Fink, Dustin M., Parins, Kia F., Doroodchi, Padydeh, Ulschmid, Caden M., Lipinski, Robert J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117230/
https://ncbi.nlm.nih.gov/pubmed/27585885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.026328
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