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Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model
Holoprosencephaly (HPE) is a common and severe human developmental abnormality marked by malformations of the forebrain and face. Although several genetic mutations have been linked to HPE, phenotypic outcomes range dramatically, and most cases cannot be attributed to a specific cause. Gene-environm...
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Publicado no: | Dis Model Mech |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5117230/ https://ncbi.nlm.nih.gov/pubmed/27585885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.026328 |
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