Gli2 gene-environment interactions contribute to the etiological complexity of holoprosencephaly: evidence from a mouse model

Holoprosencephaly (HPE) is a common and severe human developmental abnormality marked by malformations of the forebrain and face. Although several genetic mutations have been linked to HPE, phenotypic outcomes range dramatically, and most cases cannot be attributed to a specific cause. Gene-environm...

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Vydáno v:Dis Model Mech
Hlavní autoři: Heyne, Galen W., Everson, Joshua L., Ansen-Wilson, Lydia J., Melberg, Cal G., Fink, Dustin M., Parins, Kia F., Doroodchi, Padydeh, Ulschmid, Caden M., Lipinski, Robert J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117230/
https://ncbi.nlm.nih.gov/pubmed/27585885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.026328
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