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Acute and long-term outcomes in a Drosophila melanogaster model of classic galactosemia occur independently of galactose-1-phosphate accumulation

Classic galactosemia (CG) is a potentially lethal inborn error of metabolism that results from the profound loss of galactose-1-phosphate uridylyltransferase (GALT), the second enzyme in the Leloir pathway of galactose metabolism. Neonatal detection and dietary restriction of galactose minimizes or...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Daenzer, Jennifer M. I., Jumbo-Lucioni, Patricia P., Hopson, Marquise L., Garza, Kerry R., Ryan, Emily L., Fridovich-Keil, Judith L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117221/
https://ncbi.nlm.nih.gov/pubmed/27562100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.022988
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