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IGFBP1 increases β‐cell regeneration by promoting α‐ to β‐cell transdifferentiation
There is great interest in therapeutically harnessing endogenous regenerative mechanisms to increase the number of β cells in people with diabetes. By performing whole‐genome expression profiling of zebrafish islets, we identified 11 secreted proteins that are upregulated during β‐cell regeneration....
Enregistré dans:
| Publié dans: | EMBO J |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116948/ https://ncbi.nlm.nih.gov/pubmed/27516442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592903 |
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