Increased DNA methylation levels of the insulin-like growth factor binding protein 1 gene are associated with type 2 diabetes in Swedish men

BACKGROUND: Prospective studies have shown that low levels of circulating insulin-like growth factor binding protein-1 (IGFBP-1) are associated with the risk of type 2 diabetes. In the present study, we investigated DNA methylation in the IGFBP1 gene to evaluate its changes in relation to serum IGFB...

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Main Authors: Gu, Tianwei, Gu, Harvest F, Hilding, Agneta, Sjöholm, Louise K, Östenson, Claes-Göran, Ekström, Tomas J, Brismar, Kerstin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3843565/
https://ncbi.nlm.nih.gov/pubmed/24246027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-21
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