Critical role for adenosine receptor A2a in β-cell proliferation

OBJECTIVE: Pharmacological activation of adenosine signaling has been shown to increase β-cell proliferation and thereby β-cell regeneration in zebrafish and rodent models of diabetes. However, whether adenosine has an endogenous role in regulating β-cell proliferation is unknown. The objective of t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Schulz, Nadja, Liu, Ka-Cheuk, Charbord, Jérémie, Mattsson, Charlotte L., Tao, Lingjie, Tworus, Dominika, Andersson, Olov
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2016
Soggetti:
Brief Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5081418/
https://ncbi.nlm.nih.gov/pubmed/27818940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.09.006
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