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Oncogenic mechanisms of HOXB13 missense mutations in prostate carcinogenesis

The recurrent germline mutation HOXB13 p.(Gly84Glu) (G84E) has recently been identified as a risk factor for prostate cancer. In a recent study, we have performed full sequencing of the HOXB13 gene in 462 Portuguese prostate cancer patients with early-onset and/or familial/hereditary disease, and id...

詳細記述

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書誌詳細
出版年:Oncoscience
主要な著者: Cardoso, Marta, Maia, Sofia, Paulo, Paula, Teixeira, Manuel R.
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116946/
https://ncbi.nlm.nih.gov/pubmed/28050579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.322
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