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Oncogenic mechanisms of HOXB13 missense mutations in prostate carcinogenesis

The recurrent germline mutation HOXB13 p.(Gly84Glu) (G84E) has recently been identified as a risk factor for prostate cancer. In a recent study, we have performed full sequencing of the HOXB13 gene in 462 Portuguese prostate cancer patients with early-onset and/or familial/hereditary disease, and id...

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Bibliografiske detaljer
Udgivet i:Oncoscience
Main Authors: Cardoso, Marta, Maia, Sofia, Paulo, Paula, Teixeira, Manuel R.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116946/
https://ncbi.nlm.nih.gov/pubmed/28050579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncoscience.322
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