Germline Mutations in HOXB13 and Prostate-Cancer Risk

BACKGROUND: Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is poorly understood. Linkage studies have implicated chromosome 17q21-22 as a possible location of a prostate-cancer susceptibility gene. METHODS: We screened more than 200...

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Hauptverfasser: Ewing, Charles M., Ray, Anna M., Lange, Ethan M., Zuhlke, Kimberly A., Robbins, Christiane M., Tembe, Waibhav D., Wiley, Kathleen E., Isaacs, Sarah D., Johng, Dorhyun, Wang, Yunfei, Bizon, Chris, Yan, Guifang, Gielzak, Marta, Partin, Alan W., Shanmugam, Vijayalakshmi, Izatt, Tyler, Sinari, Shripad, Craig, David W., Zheng, S. Lilly, Walsh, Patrick C., Montie, James E., Xu, Jianfeng, Carpten, John D., Isaacs, William B., Cooney, Kathleen A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779870/
https://ncbi.nlm.nih.gov/pubmed/22236224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1110000
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