Germline Mutations in HOXB13 and Prostate-Cancer Risk

BACKGROUND: Family history is a significant risk factor for prostate cancer, although the molecular basis for this association is poorly understood. Linkage studies have implicated chromosome 17q21-22 as a possible location of a prostate-cancer susceptibility gene. METHODS: We screened more than 200...

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Main Authors: Ewing, Charles M., Ray, Anna M., Lange, Ethan M., Zuhlke, Kimberly A., Robbins, Christiane M., Tembe, Waibhav D., Wiley, Kathleen E., Isaacs, Sarah D., Johng, Dorhyun, Wang, Yunfei, Bizon, Chris, Yan, Guifang, Gielzak, Marta, Partin, Alan W., Shanmugam, Vijayalakshmi, Izatt, Tyler, Sinari, Shripad, Craig, David W., Zheng, S. Lilly, Walsh, Patrick C., Montie, James E., Xu, Jianfeng, Carpten, John D., Isaacs, William B., Cooney, Kathleen A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779870/
https://ncbi.nlm.nih.gov/pubmed/22236224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1110000
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