The HOXB13 G84E Mutation is Associated with an Increased Risk for Prostate Cancer and other Malignancies

BACKGROUND: A rare non-conservative substitution (G84E) in the HOXB13 gene has been shown to be associated with risk of prostate cancer. DNA samples from male patients included in the Mayo Clinic Biobank (MCB) were genotyped to determine the frequency of the G84E mutation and its association with va...

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Bibliografske podrobnosti
izdano v:Cancer Epidemiol Biomarkers Prev
Main Authors: Beebe-Dimmer, Jennifer L, Hathcock, Matthew, Yee, Cecilia, Okoth, Linda A., Ewing, Charles M, Isaacs, William B., Cooney, Kathleen A., Thibodeau, Stephen N.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560608/
https://ncbi.nlm.nih.gov/pubmed/26108461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-15-0247
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