HOXB13 G84E-related Familial Prostate Cancers: A Clinical, Histologic, and Molecular Survey

Recent genetic epidemiologic studies identified a germline mutation in the homeobox transcription factor, HOXB13 G84E, which is associated with markedly increased risk of prostate cancer, particularly early onset hereditary prostate cancer. The histomorphologic and molecular features of cancers aris...

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Autors principals: Smith, Steven C., Palanisamy, Nallasivam, Zuhlke, Kimberly A., Johnson, Anna M., Siddiqui, Javed, Chinnaiyan, Arul M., Kunju, Lakshmi P, Cooney, Kathleen A., Tomlins, Scott A.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988475/
https://ncbi.nlm.nih.gov/pubmed/24722062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000090
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