Antibody Based Detection of ERG Rearrangements in Prostate Core Biopsies, Including Diagnostically Challenging Cases

CONTEXT: Fusions of androgen-regulated genes and v-ets erythroblastosis virus E26 oncogene homolog (avian) (ERG) occur in ~50% of prostate cancers, encoding a truncated ERG product. In prostatectomy specimens, ERG-rearrangements are >99% specific for prostate cancer or high grade prostatic intrae...

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Hlavní autoři: Tomlins, Scott A., Palanisamy, Nallasivam, Siddiqui, Javed, Chinnaiyan, Arul M., Kunju, Lakshmi P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667408/
https://ncbi.nlm.nih.gov/pubmed/22849743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5858/arpa.2011-0424-OA
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