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Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi

Trypanosoma cruzi is the causative agent of chronic chagasic cardiomyopathy. Why macrophages (mφs), the early responders to infection, fail to achieve parasite clearance is not known. Mouse (RAW 264.7) and human (THP-1 and primary) mφs were infected for 3 h and 18 h with T. cruzi TcI isolates, Sylvi...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Koo, Sue-jie, Chowdhury, Imran H., Szczesny, Bartosz, Wan, Xianxiu, Garg, Nisha J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116729/
https://ncbi.nlm.nih.gov/pubmed/27698021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00809-16
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