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Macrophages Promote Oxidative Metabolism To Drive Nitric Oxide Generation in Response to Trypanosoma cruzi

Trypanosoma cruzi is the causative agent of chronic chagasic cardiomyopathy. Why macrophages (mφs), the early responders to infection, fail to achieve parasite clearance is not known. Mouse (RAW 264.7) and human (THP-1 and primary) mφs were infected for 3 h and 18 h with T. cruzi TcI isolates, Sylvi...

詳細記述

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書誌詳細
出版年:Infect Immun
主要な著者: Koo, Sue-jie, Chowdhury, Imran H., Szczesny, Bartosz, Wan, Xianxiu, Garg, Nisha J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116729/
https://ncbi.nlm.nih.gov/pubmed/27698021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00809-16
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