Endotoxin free hyaluronan and hyaluronan fragments do not stimulate TNF-α, interleukin-12 or upregulate co-stimulatory molecules in dendritic cells or macrophages

The extracellular matrix glycosaminoglycan, hyaluronan, has been described as a regulator of tissue inflammation, with hyaluronan fragments reported to stimulate innate immune cells. High molecular mass hyaluronan is normally present in tissues, but upon inflammation lower molecular mass fragments a...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Dong, Yifei, Arif , Arif, Olsson, Mia, Cali, Valbona, Hardman, Blair, Dosanjh, Manisha, Lauer, Mark, Midura, Ronald J., Hascall, Vincent C., Brown, Kelly L., Johnson, Pauline
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5116629/
https://ncbi.nlm.nih.gov/pubmed/27869206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36928
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