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Comparison of Liver Cell Models Using the Basel Phenotyping Cocktail
Currently used hepatocyte cell systems for in vitro assessment of drug metabolism include hepatoma cell lines and primary human hepatocyte (PHH) cultures. We investigated the suitability of the validated in vivo Basel phenotyping cocktail (caffeine [CYP1A2], efavirenz [CYP2B6], losartan [CYP2C9], om...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5116554/ https://ncbi.nlm.nih.gov/pubmed/27917125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00443 |
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